Lymph node injections offer fast allergy therapy
NEW YORK (Reuters Health) - Direct administration of an allergen - the substance that triggers an allergic reaction — into the lymph nodes, rather than the skin, reduces both the number and dose of injections required to induce tolerance to the offending substance, researchers report. This appears to offer a rapid, save and effective way to treat IgE-mediated allergies.
We demonstrated that this approach enhanced safety, efficacy, and compliance. The procedure allowed “reduction of the number of injections from 54 to 3, and reduction in the cumulative allergen dose by more than 1000-fold,” Dr. Thomas M. Kundig from University Hospital Zurich, Switzerland, and colleagues write in the Proceedings of the National Academy of Science.